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| Cat. Number | 287221257673925 |
| Chemical Name | AMN 082 dihydrochloride |
| CAS Number | [83027-13-8] |
| Mol. Formula | C28H28N2.2HCl |
| Mol. Weight | 465.45 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N,N'-Bis(diphenylmethyl)-1,2-ethaned iamine dihydrochloride |
| Solubility | Soluble to 100 mM in DMSO and to 10 mM in methanol |
| Storage condition | Desiccate at +4°C |
| References | The first selective mGlu7 agonist. Potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μM. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats. Purity: >99 % |
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