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/ Products Classification 点击展开+Cat. Number | 287204719927263 |
Chemical Name | Amisulpride |
CAS Number | [71675-85-9] |
Mol. Formula | C17H27N3O4S |
Mol. Weight | 369.48 |
Qty 1 |
50mg |
Synonym | 4-Amino-N-[(1-ethyl-2-pyrrolidinyl) methyl]-5-(ethylsulfonyl)-2-benzamide |
Solubility | Soluble to 25 mM in 1eq. HCl and to 50 mM in DMSO |
Storage condition | Store at -20°C |
References | Potent, selective dopamine D2 and D3 receptor antagonist. Ki values are 2.8 and 3.2 nM respectively for human D2 and D3 and > 1000 nM for human D1, D4 and D5 receptors. Shows selectivity for presynaptic dopamine autoreceptors at low doses and blocks postsynaptic D2/D3 receptors at higher doses. Preferentially interacts with limbic D2-like receptors in vivo. Atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects and a profile distinct from that of haloperidol and remoxipride. Purity: >98 % |