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| Cat. Number | 287179728559414 |
| Chemical Name | Aminopurvalanol A |
| CAS Number | [220792-57-4] |
| Mol. Formula | C19H26ClN7O |
| Mol. Weight | 403.91 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (2R)-2-[[6-[(3-Amino-5-chlorophenyl )amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-m ethyl-1-butanol |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Cell-permeable cyclin-dependent kinase inhibitor. IC50 values are 0.033, 0.033, 0.028 and 0.020 μM for cdk1/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5/p35 respectively. Inhibits ERK1 (IC50 = 12.0 μM) and ERK2 (IC50 = 3.1 μM) and is 3000-fold selective over a range of other protein kinases (IC50 > 100 μM). Arrests cell cycle at G2/M boundary (IC50 = 1.25 μM), and induces apoptosis at concentrations > 10 μM. Purity: >98 % |
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