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| Cat. Number | 286680890254876 |
| Chemical Name | AG 18 |
| CAS Number | [118409-57-7] |
| Mol. Formula | C10H6N2O2 |
| Mol. Weight | 186.17 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | [(3,4-Dihydroxyphenyl)methylene]-pr openedinitrile |
| Storage condition | Desiccate at +4°C |
| References | Inhibitor of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase (IC50 values are 35 and 25 μM respectively). Inhibits EGF-stimulated cell proliferation. Also acts as a mitochondrial uncoupler that alters phosphorylation-dependent cell signaling. |
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