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| Cat. Number | 286650961280631 |
| Chemical Name | AEG 3482 |
| CAS Number | [63735-71-7] |
| Mol. Formula | C10H8N4O2S2 |
| Mol. Weight | 280.33 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 6-Phenylimidazo[2,1-b]-1,3,4-thiadi azole-2-sulfonamide |
| Solubility | Soluble to 100 mM in DMSO and to 5 mM in ethanol |
| Storage condition | Store at RT |
| References | Inhibitor of c-jun N-terminal kinase (JNK) signaling. Binds Hsp90 and facilitates HSF1 release, induces expression of Hsp70, which in turn blocks JNK activation and JNK-dependent apoptosis. Antiapoptotic; inhibits NGF withdrawal-induced death in SCG neurons (EC50 = 20 μM). Purity: >99 % |
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