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Cat. Number
286150232943315
Chemical Name
A 987306
CAS Number
[1082954-71-9]
Mol. Formula
C18H25N5O
Mol. Weight
327.42
Qty 1
10mg
Qty 2
50mg
Synonym
(±)-(7aR*,11aR*)-5,6,7a,8,9,10,11,11 a-Octahydro-4-(1-piperazinyl)-benzofuran[2,3-h]qui nazolin-2-amine
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage condition
Store at -20°C
References
Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo (ED50 = 42 μmol/kg, ip).
Purity: >98 %
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