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/ Products Classification 点击展开+Cat. Number | 286150232943315 |
Chemical Name | A 987306 |
CAS Number | [1082954-71-9] |
Mol. Formula | C18H25N5O |
Mol. Weight | 327.42 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (±)-(7aR*,11aR*)-5,6,7a,8,9,10,11,11 a-Octahydro-4-(1-piperazinyl)-benzofuran[2,3-h]qui nazolin-2-amine |
Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
Storage condition | Store at -20°C |
References | Potent histamine H4 receptor antagonist (pKi values are 8.24 and 8.47 in human and rat H4 receptors respectively). Displays 162-fold, 620-fold, and > 1600-fold selectivity over human H3, H1 and H2 receptors. Blocks zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo (ED50 = 42 μmol/kg, ip). Purity: >98 % |