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Cat. Number
286116588916349
Chemical Name
A 803467
CAS Number
[944261-79-4]
Mol. Formula
C19H16ClNO4
Mol. Weight
357.79
Qty 1
10mg
Qty 2
50mg
Synonym
5-(4-Chlorophenyl)-N-(3,5-dimethoxy phenyl)-2-furancarboxamide
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at +4°C
References
Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Antinociceptive; potently attenuates mechanical allodynia in two models of neuropathic pain following i.p. administration.
Purity: >98 %
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