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| Cat. Number | 285410724144417 |
| Chemical Name | BVT 948 |
| CAS Number | [39674-97-0] |
| Mol. Formula | C14H11NO3 |
| Mol. Weight | 241.25 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-Hydroxy-3,3-dimethyl-2H-benz[g]in dole-2,5(3H)-dione |
| Solubility | Soluble to 50 mM in ethanol and to 50 mM in DMSO |
| Storage condition | Store at RT |
| References | Non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM); displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. Enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Also inhibits several cytochrome P450 isoforms (IC50 < 10 μM). Purity: >98 % |
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