服务热线
021-60498804
| Cat. Number | 285010962234639 |
| Chemical Name | BMS 299897 |
| CAS Number | [290315-45-6] |
| Mol. Formula | C24H21ClF3NO4S |
| Mol. Weight | 511.94 |
| Qty 1 |
10mg |
| Synonym | 2-[(1R)-1-[[(4-Chlorophenyl)sulfony l](2,5-difluorophenyl)amino]ethyl-5-fluorobenzeneb utanoic acid |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at -20°C |
| References | Orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Exhibits no Notch toxicity. Brain penetrant. Purity: >98 % |
下一个：BMS 453上一个：BMS 193885 |
|
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
