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Cat. Number
284986231792790
Chemical Name
BMS 182874 hydrochloride
CAS Number
[153042-42-3]
Mol. Formula
C17H19N3O3S.HCl
Mol. Weight
381.88
Qty 1
10mg
Qty 2
50mg
Synonym
5-(Dimethylamino)-N-(3,4-dimethyl-5 -isoxazolyl)-1-naphthalenesulfonamide hydrochloride
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Potent, selective and competitive non-peptide endothelin ETA receptor antagonist (Ki = 48 nM). Displays > 1000-fold selectivity over ETB receptors. Inhibits ET-1-induced pressor response following oral or intravenous administration in vivo. Inhibits ET-1-induced longitudinal muscle contraction in the mouse colon in vitro.
Purity: >98 %
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