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| Cat. Number | 284401490065680 |
| Chemical Name | BAG 956 |
| CAS Number | [853910-02-8] |
| Mol. Formula | C28H21N5 |
| Mol. Weight | 427.5 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | α,α,-Dimethyl-4-[2-methyl-8-[2-(3-pyr idinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-be nzeneacetonitrile |
| Solubility | Soluble to 40 mM in DMSO and to 20 mM in ethanol |
| Storage condition | Store at RT |
| References | Dual PDK1 and class I PI3K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDK1 and PI3K p110 -α, -β, -δ, and -γ respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models. Purity: >99 % |
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