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| Cat. Number | 283324358731166 |
| Chemical Name | Compound 401 |
| CAS Number | [168425-64-7] |
| Mol. Formula | C16H15N3O2 |
| Mol. Weight | 281.31 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-(4-Morpholinyl)-4H-pyrimido[2,1-a ]isoquinolin-4-one |
| Solubility | Soluble to 10 mM in DMSO and to 5 mM in ethanol |
| Storage condition | Store at RT |
| References | Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC50 values are 0.28 and 5.3 μM respectively). Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC50 values are all > 100 μM). Induces apoptosis in vitro. Purity: >99 % |
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