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Cat. Number
283086126884322
Chemical Name
CITCO
Mol. Formula
C19H12Cl3N3OS
Mol. Weight
436.74
Qty 1
10mg
Qty 2
50mg
Synonym
6-(4-Chlorophenyl)imidazo[2,1-b][1, 3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)ox ime
Solubility
Soluble to 50 mM in DMSO and to 5 mM in ethanol
Storage condition
Desiccate at -20°C
References
Constitutive androstane receptor (CAR) agonist (EC50 = 49 nM). Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ERα, ERβ, PPAR, RAR, FXR, VDR and THR. Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro.
Purity: >98 %
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