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/ Products Classification 点击展开+Cat. Number | 283086126884322 |
Chemical Name | CITCO |
Mol. Formula | C19H12Cl3N3OS |
Mol. Weight | 436.74 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 6-(4-Chlorophenyl)imidazo[2,1-b][1, 3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)ox ime |
Solubility | Soluble to 50 mM in DMSO and to 5 mM in ethanol |
Storage condition | Desiccate at -20°C |
References | Constitutive androstane receptor (CAR) agonist (EC50 = 49 nM). Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ERα, ERβ, PPAR, RAR, FXR, VDR and THR. Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro. Purity: >98 % |