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Cat. Number
282998862986665
Chemical Name
Cilastatin sodium
CAS Number
[81129-83-1]
Mol. Formula
C16H25N2NaO5S
Mol. Weight
380.43
Qty 1
10mg
Qty 2
50mg
Synonym
(2Z)-7-[[(2R)-2-Amino-2-carboxyethy l]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl ]amino]-2-heptenoic acid sodium salt
Solubility
Soluble to 100 mM in water and to 10 mM in DMSO
Storage condition
Desiccate at -20°C
References
Dipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a Ki value of 0.11 μM. Inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. Nephroprotective; reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells.
Purity: >99 %
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