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Cat. Number
282941497984199
Chemical Name
(-)-[3R,4S]-Chromanol 293B
CAS Number
[163163-24-4]
Mol. Formula
C15H20N2O4S
Mol. Weight
324.39
Qty 1
10mg
Qty 2
50mg
Synonym
N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hy droxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyle thanesulfonamide
Solubility
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at RT
References
Enantiomer that selectively inhibits the slow component of delayed rectifier K+ current (IKs). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC50 values are 1.36 and 9.6 μM respectively). Has negligible inhibitory action at hERG channels (IC50 > 30 μM). Racemate Chromanol 293B (Cat. No. 1412) also available.
Purity: >99 %
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