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Cat. Number
282606742048033
Chemical Name
CGP 53353
CAS Number
[145915-60-2]
Mol. Formula
C20H13F2N3O2
Mol. Weight
365.34
Qty 1
10mg
Synonym
5,6-bis[(4-Fluorophenyl)amino]-1H-i soindole-1,3(2H)-dione
Solubility
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage condition
Store at RT
References
Selective inhibitor of PKCβII (IC50 values are 0.41 and 3.8 μM for PKCβII and PKCβI respectively). Also inhibits prionogenic Sup35 fibrillization (IC50 ~ 3.4 μM) and inhibits de novo Aβ42 assembly in vitro.
Purity: >99 %
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