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Cat. Number
282590144734798
Chemical Name
CGP 52411
CAS Number
[145915-58-8]
Mol. Formula
C20H15N3O2
Mol. Weight
329.35
Qty 1
10mg
Qty 2
50mg
Synonym
5,6-Bis(phenylamino)-1H-isoindole-1 ,3(2H)-dione
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage condition
Store at RT
References
Selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Also inhibits and reverses the formation of Aβ42 fibers associated with Alzheimer's disease. Eliminates calcium influx potential when coincubated with amyloid β-peptide (1-42) (Cat.No. 1428); reduces neurotoxicity by blocking Ca2+ influx into neuronal cells.
Purity: >99 %
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