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Cat. Number
279574353031302
Chemical Name
DPO-1
CAS Number
[43077-30-1]
Mol. Formula
C22H29OP
Mol. Weight
340.44
Qty 1
10mg
Qty 2
50mg
Synonym
[1S-(1α,2α,5β)]-[5-Methyl-2-(1-methyle thyl)cyclohexyl]diphenylphosphine oxide
Solubility
Soluble to 100 mM in ethanol
Storage condition
Store at +4°C
References
Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels (IC50 = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IKur over Ito (8-fold), IK1, IKr and IKs (20-fold) in native myocytes and selectivity for rat recombinant KV1.5 over KV3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.
Purity: >99 %
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