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| Cat. Number | 279374511306987 |
| Chemical Name | DMP 543 |
| CAS Number | [160588-45-4] |
| Mol. Formula | C26H18F2N2O |
| Mol. Weight | 412.44 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 10,10-bis[(2-Fluoro-4-pyridinyl)met hyl]-9(10H)-anthracenone |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at RT |
| References | K+ channel blocker and acetylcholine release stimulator. Potently enhances K+-stimulated [3H]-ACh release from rat hippocampal slices (EC50 = 700 nM), and also increases release of dopamine and glutamate (EC50 values are 0.25 and 0.22 μM, respectively). Orally active in vivo; increases ACh levels in rats (with a minimum effective dose of 1 mg/kg) and exerts a long duration of action. More potent than linopirdine (Cat. No. 1999) both in vitro and in vivo. Purity: >99 % |
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