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| Cat. Number | 279339350118254 |
| Chemical Name | 17-DMAG hydrochloride |
| CAS Number | [467214-20-6] |
| Mol. Formula | C32H48N4O8.HCl |
| Mol. Weight | 653.21 |
| Qty 1 |
1mg |
| Synonym | 17-Demethoxy-17-[[2-(dimethylamino) ethyl]amino]geldanamycin hydrochloride |
| Solubility | Soluble to 30 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Water-soluble analog of 17-AAG (Cat. No. 1515) and geldanamycin (Cat. No. 1368). Binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively). Purity: >99 % |
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