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Cat. Number
279185692745961
Chemical Name
Dihydroergotoxine mesylate
CAS Number
[8067-24-1]
Qty 1
100mg
Solubility
Soluble in ethanol
Storage condition
Store at RT
References
A complex of closely related alkaloid salts. Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site. Also interacts with central dopaminergic, serotonergic and adrenergic (α1) receptors. Displays antiproliferative activity in vitro (IC50 = 18 - 38 μM in prostate cancer cells) and exhibits cognition-enhancing, anticonvulsant and sedative activity in vivo. Orally active.
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