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| Cat. Number | 278905524615495 |
| Chemical Name | DCA |
| CAS Number | [2156-56-1] |
| Mol. Formula | C2HCl2NaO2 |
| Mol. Weight | 150.92 |
| Qty 1 |
100mg |
| Synonym | Dichloroacetate |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulation of KV1.5 channels in cancer but not normal cells. Decreases tumor growth in vitro and in vivo. |
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