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Cat. Number
278842603482872
Chemical Name
D 4476
CAS Number
[301836-43-1]
Mol. Formula
C23H18N4O3
Mol. Weight
398.41
Qty 1
10mg
Qty 2
50mg
Synonym
4-[4-(2,3-Dihydro-1,4-benzodioxin-6 -yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at +4°C
References
Selective inhibitor of casein kinase 1 (CK1) and TGF-β type-I receptor (ALK5) that displays > 20-fold selectivity over SAPK2/p38 and a much greater selectivity over all other protein kinases tested. Suppresses site-specific phosphorylation and nuclear exclusion of FOXO1a.
Purity: >99 %
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