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| Cat. Number | EX 527 |
| Chemical Name | EX 527 |
| CAS Number | [49843-98-3] |
| Mol. Formula | C13H13ClN2O |
| Mol. Weight | 248.71 |
| Qty 1 |
1mg |
| Qty 2 | 50mg |
| Synonym | 6-Chloro-2,3,4,9-tetrahydro-1H-carb azole-1-carboxamide |
| Solubility | Soluble to 75 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Enhances p53 acetylation in response to DNA damaging agents. Purity: >98 % |
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