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Cat. Number
Enterostatin
Chemical Name
Enterostatin
CAS Number
[117830-79-2]
Mol. Formula
C21H36N8O6
Mol. Weight
496.57
Qty 1
1mg
Storage condition
Store at -20°C
References
N' terminal peptide fragment of procolipase that binds to the β-subunit of F1-ATPase. Activates the ERK and cAMP signaling pathways, and downregulates expression of Krüppel-like factor 4 (KLF4) and agouti-related peptide (AgRP) in vitro. Inhibits insulin secretion from pancreatic β-cells by downregulating expression of dynamin2 and altering protein trafficking. Reduces dietary fat intake via activation of CCK1, induces satiety, enhances memory-consolidation and exhibits hypocholesterolemic activity in vivo. Orally active.
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