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Cat. Number
FTI 276
Chemical Name
FTI 276
CAS Number
[170006-72-1]
Mol. Formula
C21H27N3O3S2.C2HF3O2
Mol. Weight
547.61
Qty 1
1mg
Synonym
N-[4-[2(R)-Amino-3-mercaptopropyl]a mino-2-phenylbenzoyl]methionine trifluoroacetate salt
Solubility
Soluble to 10 mM in water
Storage condition
Store at -80°C
References
Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) that displays > 100-fold selectivity over geranylgeranyltransferase I (GGTase I) (IC50 values are 0.5 and 50 nM respectively). Blocks growth of human lung carcinoma expressing oncogenic K-Ras in nude mice.
Purity: >95 %
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