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| Cat. Number | 5'-Fluoroindirubinoxime |
| Chemical Name | 5'-Fluoroindirubinoxime |
| CAS Number | [861214-33-7] |
| Mol. Formula | C16H10FN3O2 |
| Mol. Weight | 295.27 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5'-Fluoro-1H,1'H-[2,3']biindolylidene- 3,2'dione 3-oxime |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3) (IC50 = 15 nM). Displays selectivity for FMT3 against 6 other kinases including EGFR. Displays antiproliferative activity against the MV4;11 cell line (expressing constitutively active FLT3) and a number of cancer cell lines, including SNU-638 (stomach carcinoma) and HT-1080 (fibrosarcoma). Purity: >99 % |
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