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| Cat. Number | FK 888 |
| Chemical Name | FK 888 |
| CAS Number | [138449-07-7] |
| Mol. Formula | C36H36N4O4 |
| Mol. Weight | 588.69 |
| Qty 1 |
10mg |
| Synonym | (4R)-4-Hydroxy-1-[(1-methyl-1H-indo l-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalen yl)-N-(phenylmethyl)-L-alaninamide |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at -20°C |
| References | Selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors. Inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration. Purity: >98 % |
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