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| Cat. Number | FAK Inhibitor 14 |
| Chemical Name | FAK Inhibitor 14 |
| CAS Number | [4506-66-5] |
| Mol. Formula | C6H10N4.4HCl |
| Mol. Weight | 284.01 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1,2,4,5-Benzenetetramine tetrahydrochloride |
| Solubility | Soluble to 50 mM in water and to 75 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. |
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