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| Cat. Number | GYKI 53655 hydrochloride |
| Chemical Name | GYKI 53655 hydrochloride |
| CAS Number | [143692-48-2] |
| Mol. Formula | C19H20N4O3.HCl |
| Mol. Weight | 388.85 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-(4-Aminophenyl)-3-methylcarbamyl- 4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-ben zodiazepine hydrochloride |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Non-competitive AMPA and kainate receptor antagonist. Analog of GYKI 52466 (Cat. No. 1454). Prolongs the survival time after MgCl2- induced global cerebral ischemia. Exhibits anticonvulsant activity. Also blocks GluK3 homomeric receptors (IC50 = 63 μM) and GluK2b(R)/GluK3 heteroreceptors (IC50 = 32 μM) at high concentrations. Purity: >99 % |
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