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Cat. Number
GSK 4112
Chemical Name
GSK 4112
Mol. Formula
C18H21ClN2O4S
Mol. Weight
396.89
Qty 1
10mg
Qty 2
50mg
Synonym
1,1-Dimethylethyl-N-[(4-chloropheny l)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate
Solubility
Soluble to 25 mM in DMSO
Storage condition
Store at +4°C
References
Selective REV-ERBα agonist (EC50 = 250 nM). Enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to REV-ERBα; causes acute suppression of Bmal1 gene transcription. Induces phase shifts in the circadian clock.
Purity: >98 %
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