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| Cat. Number | GR 159897 |
| Chemical Name | GR 159897 |
| CAS Number | [158848-32-9] |
| Mol. Formula | C23H27FN2O2S |
| Mol. Weight | 414.54 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-ph enylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indo le |
| Solubility | Soluble to 50 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | A potent, selective, non-peptide, orally active neurokinin NK2 receptor antagonist. Competes for binding of [3H]GR100679 to hNK2-transfected CHO cells with a pKi of 9.5. Inhibits NK2 receptor-mediated contraction of guinea pig trachea with a pA2 of 8.7. Anxiolytic in vivo. Purity: >97 % |
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