服务热线
021-60498804
产品中心
/ Products Classification 点击展开+Cat. Number | GBR 12909 dihydrochloride |
Chemical Name | GBR 12909 dihydrochloride |
CAS Number | [67469-78-7] |
Mol. Formula | C28H32F2N2O.2HCl |
Mol. Weight | 523.49 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 1-[2-[Bis-(4-fluorophenyl)methoxy]e thyl]-4-(3-phenylpropyl)piperazine dihydrochloride |
Solubility | Soluble to 5 mM in water and to 50 mM in DMSO |
Storage condition | Desiccate at RT |
References | Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. Purity: >98 % |