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Cat. Number
GBR 12909 dihydrochloride
Chemical Name
GBR 12909 dihydrochloride
CAS Number
[67469-78-7]
Mol. Formula
C28H32F2N2O.2HCl
Mol. Weight
523.49
Qty 1
10mg
Qty 2
50mg
Synonym
1-[2-[Bis-(4-fluorophenyl)methoxy]e thyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Solubility
Soluble to 5 mM in water and to 50 mM in DMSO
Storage condition
Desiccate at RT
References
Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.
Purity: >98 %
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