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| Cat. Number | G-1 |
| Chemical Name | G-1 |
| CAS Number | [881639-98-1] |
| Mol. Formula | C21H18BrNO3 |
| Mol. Weight | 412.28 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1, 3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclop enta[c]quinolin-8-yl]- ethanone |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent and selective GPR30 receptor agonist (Ki = 11 nM, EC50 = 2 nM); displays no activity at ERα and ERβ at concentrations up to 10 μM. Increases cytosolic Ca2+ and inhibits migration of SKBr3 cells and MCF-7 cells in response to chemoattractants (IC50 values are 0.7 and 1.6 nM respectively) in vitro. Blocks MCF-1 cell cycle progression at the G1 phase. Displays therapeutic effects in the mouse EAE model of multiple sclerosis. Purity: >99 % |
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