服务热线
021-60498804
| Cat. Number | HU 211 |
| Chemical Name | HU 211 |
| CAS Number | [112924-45-5] |
| Mol. Formula | C25H38O3 |
| Mol. Weight | 386.57 |
| Synonym | (6aS,10aS)-3-(1,1-Dimethylheptyl)-6 a,77,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-d ibenzo[b,d]pyran-9-methanol |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at -20°C |
| References | NMDA antagonist (IC50 = 11 μM for inhibition of [3H]MK-801 binding to rat forebrain membranes). Protects against NMDA- and quisqualate-induced neurotoxicity (EC50 = 3.8 μM) and enhances dopamine D1 receptor activity. Inhibits NF-κB, reducing TNF-α, IL-6 and nitric oxide production, and acts as a free radical scavenger. Exhibits beneficial effects in experimental models of multiple sclerosis, bacterial meningitis, septic shock, epilepsy, and traumatic and ischemic brain injury. Brain penetrant. Purity: >97 % |
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
