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/ Products Classification 点击展开+Cat. Number | 4-HQN |
Chemical Name | 4-HQN |
CAS Number | [491-36-1] |
Mol. Formula | C8H6N2O |
Mol. Weight | 146.15 |
Qty 1 |
50mg |
Synonym | 4-(1H)-Quinazolinone |
Solubility | Soluble to 10 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at RT |
References | Inhibitor of poly(ADP-ribose) polymerase (PARP) (IC50 = 9.5 μM); displays mixed inhibition with respect to NAD+. Protective against ischemia-reperfusion induced ROS production, and subsequent mitochondrial and cell damage in rat heart. Anti-inflammatory in LPS-induced endotoxic mice in vivo; decreases NF-κB and AP-1 activation. Purity: >99 % |