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Cat. Number
Harmane
Chemical Name
Harmane
CAS Number
[486-84-0]
Mol. Formula
C12H10N2
Mol. Weight
182.22
Qty 1
100mg
Synonym
1-Methyl-9H-pyrido[3,4-b]indole hydrochloride
Solubility
Soluble to 10 mM in 1eq. HCl
Storage condition
Store at RT
References
Proposed as the endogenous ligand for imidazoline binding sites. Binds to I1-sites in rat kidney (IC50 = 31 nM) and I2-sites (Ki = 49 nM). Produces dose-dependent hypotension in vivo that is reversed by efaroxan (Cat. No. 0792). Potent inhibitor of monoamine oxidase A and B (IC50 values are 0.5 and 5 μM respectively).
Purity: >99 %
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