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| Cat. Number | HA14-1 |
| Chemical Name | HA14-1 |
| CAS Number | [65673-63-4] |
| Mol. Formula | C17H17BrN2O5 |
| Mol. Weight | 409.23 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-Amino-6-bromo-α-cyano-3-(ethoxycar bonyl)-4H-1-benzopyran-4-acetic acid ethyl ester |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 μM); acts by binding to the surface pocket. Disrupts Bax/Bcl-2 interaction and induces apoptosis of tumor cells. Also binds to the antiapoptotic Blc-2 proteins Bcl-XL and Bcl-w. |
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