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| Cat. Number | 5-Iodotubercidin |
| Chemical Name | 5-Iodotubercidin |
| CAS Number | [24386-93-4] |
| Mol. Formula | C11H13IN4O4 |
| Mol. Weight | 392.15 |
| Qty 1 |
1mg |
| Synonym | 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrol o[2,3-d]pyrimidin-4-amine |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent adenosine kinase inhibitor (IC50 = 26 nM) and nucleoside transporter inhibitor (IC50 values are 7, 15 and < 25 nM for inhibition of [3H]-uridine, [3H]-formycin B and [3H]-adenosine uptake respectively). Strongly stimulates glycogen synthesis in hepatocytes via activation of glycogen synthase. Also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC (IC50 values are 0.4, 3.5, 5-10, 5-10, 10.9 and 27.7 μM respectively). Purity: >90 % |
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