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| Cat. Number | INCA-6 |
| Chemical Name | INCA-6 |
| CAS Number | [3519-82-2] |
| Mol. Formula | C20H12O2 |
| Mol. Weight | 284.31 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 9,10-Dihydro-9,10[1',2']-benzenoanthr acene-1,4-dione |
| Solubility | Soluble to 20 mM in DMSO |
| Storage condition | Store at RT |
| References | Inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (Kd = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT. Purity: >98 % |
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