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| Cat. Number | IEM 1460 |
| Chemical Name | IEM 1460 |
| CAS Number | [121034-89-7] |
| Mol. Formula | C19H37N2Br.HBr |
| Mol. Weight | 454.33 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N,N,H,-Trimethyl-5-[(tricyclo[3.3.1 .13,7]dec-1-ylmethyl)amino]-1-pentanaminiumbromide hydrobromide |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Voltage-dependent open-channel blocker of AMPA receptors. Displays selectivity between subtypes, blocking GluR2 subunit-lacking (Ca2+-permeable) receptors more potently than GluR2-containing receptors (IC50 values are 2.6 and 1102 μM respectively). Also blocks NMDA receptor-mediated currents. Anticonvulsant in vivo. |
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