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| Cat. Number | JTE 013 |
| Chemical Name | JTE 013 |
| CAS Number | [547756-93-4] |
| Mol. Formula | C17H19N7OCl2 |
| Mol. Weight | 408.29 |
| Qty 1 |
10mg |
| Synonym | 1-[1,3-Dimethyl-4-(2-methylethyl)-1 H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-p yridinyl)-semicarbazide |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P2 (EDG-5). Inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. At concentrations up to 10 μM, displays 4.2% inhibition of S1P3 and does not antagonize S1P1. Enhances S1P-induced angiogenesis in vivo. Purity: >98 % |
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