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| Cat. Number | JNJ 5207852 dihydrochloride |
| Chemical Name | JNJ 5207852 dihydrochloride |
| CAS Number | [398473-34-2] |
| Mol. Formula | C20H32N2O.2HCl |
| Mol. Weight | 389.4 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-[3-[4-(1-Piperidinylmethyl)phenox y]propyl]piperidine hydrochloride |
| Solubility | Soluble to 50 mM in water and to 20 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | High affinity histamine H3 receptor neutral antagonist (pKi values are 8.9 and 9.2 in rat and human respectively). Brain penetrant and orally active. Has 3- and 100-fold higher affinity than thioperamide (Cat. No. 0644) for rat and human H3 receptors respectively. Suppresses slow-wave sleep; exhibits wake-promoting effects in rodent arousal models. Purity: >99 % |
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