服务热线
021-60498804
| Cat. Number | JNJ 28871063 hydrochloride |
| Chemical Name | JNJ 28871063 hydrochloride |
| CAS Number | [944341-54-2] |
| Mol. Formula | C24H27CIN6O3.HCl |
| Mol. Weight | 519.42 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5E-4-Amino-6-(4-benzyloxy-3-chlorop henylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Potent and selective ErbB receptor family inhibitor (IC50 values are 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively). Displays potent growth inhibition of human cancer cell lines overexpressing ErbB2 in vitro (IC50 = 60 - 168 nM) and inhibits growth of human tumor xenografts in vivo. Brain penetrant and orally active. Purity: >97 % |
下一个：JNJ 303上一个：JNJ 17203212 |
|
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
