服务热线
021-60498804
| Cat. Number | JK 184 |
| Chemical Name | JK 184 |
| CAS Number | [315703-52-7] |
| Mol. Formula | C19H18N4OS |
| Mol. Weight | 350.44 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-(4-Ethoxyphenyl)-4-(2-methylimida zo[1,2-a]pyridin-3-yl)-2-thiazolamine |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Exhibits antiproliferative activity in a range of cancer cell lines (GI50 = 3 - 21 nM) and in human xenografts in vivo. Inhibits alcohol dehydrogenase 7 (Adh7) (IC50 = 210 nM) and acts as a microtubule depolymerizing agent in vitro. Purity: >99 % |
下一个：JLK 6上一个：JIP-1 (153-163) |
|
Copyright © 2022 上海惠诚生物科技有限公司
沪ICP备2021037845号-6
