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| Cat. Number | Ko 143 |
| Chemical Name | Ko 143 |
| CAS Number | [461054-93-3] |
| Mol. Formula | C26H36N3O5 |
| Mol. Weight | 469.57 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Synonym | (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Oct ahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyraz ino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester |
| Solubility | Soluble to 50 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at -20°C |
| References | Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. Purity: >99 % |
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