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| Cat. Number | Ki 8751 |
| Chemical Name | Ki 8751 |
| CAS Number | [228559-41-9] |
| Mol. Formula | C24H18F3N3O4 |
| Mol. Weight | 469.41 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-(2,4-Difluorophenyl)-N'-[4-[(6,7-d imethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent, selective inhibitor of VEGFR-2 tyrosine kinase (IC50 = 0.9 nM). Displays some inhibitory activity towards c-Kit, PDGFRα and FGFR-2 (IC50 values range from 40 to 170 nM) but is highly selective over other receptor tyrosine kinases (IC50 > 10000 nM for FGFR-2, EGFR and HGFR). Inhibits VEGF-stimulated proliferation of human umbilical vein endothelial cells (HUVEC) and inhibits tumor growth in vivo; antiangiogenic. Purity: >97 % |
下一个：Kifunensine上一个：KH 7 |
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