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| Cat. Number | K-252c |
| Chemical Name | K-252c |
| CAS Number | [85753-43-1] |
| Mol. Formula | C20H13N3O |
| Mol. Weight | 311.34 |
| Qty 1 |
1mg |
| Synonym | 6,7,12,13-Tetrahydro-5H-indolo[2,3- a]pyrrolo[3,4-c]carbazol-5-one |
| Solubility | Soluble to 25 mM in DMSO |
| Storage condition | Store at -20°C |
| References |
Inhibitor of protein kinase C (IC50 = 2.45 μM) that displays ~ 10-fold selectivity over protein kinase A (IC50 = 25.7 μM). Also inhibits β-lactamase, malate dehydrogenase and chymotrypsin (IC50 values are 8, 8 and 10 μM respectively). Exhibits antiviral activity against GCV-sensitive and -resistant strains of human cytomegalovirus (HCMV) (IC50 values range from 0.13 - 0.32 μM). Shows no activity against herpes simplex virus (HSV). |
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