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| Cat. Number | K 858 |
| Chemical Name | K 858 |
| CAS Number | [72926-24-0] |
| Mol. Formula | C13H15N3O2S |
| Mol. Weight | 277.34 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-(4-Acetyl-4,5-dihydro-5-methyl-5- phenyl-1,3,4-thiadiazol-2-yl)acetamide |
| Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC50 = 1.3 μM). Induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells. Displays no effect on microtubule dynamics. Preferentially induces mitotic arrest in cancer cells. Purity: >99 % |
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