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Cat. Number
LY 487379 hydrochloride
Chemical Name
LY 487379 hydrochloride
CAS Number
[353231-17-1]
Mol. Formula
C21H19F3N2O4S.HCl
Mol. Weight
488.91
Qty 1
10mg
Qty 2
50mg
Synonym
2,2,2-Trifluoro-N-[4-(2-methoxyphen oxy)phenyl]-N-(3-pyridinylmethyl)ethanesulfonamide hydrochloride
Solubility
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage condition
Store at -20°C
References
Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors. Promotes cognitive flexibility in a rat model.
Purity: >99 %
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